Ingredient Profile - Tyrosinase Inhibitors

Ingredient Profile - Tyrosinase Inhibitors

Katie Marshall

Hyperpigmentation is a stubborn skin issue with many causes:

  • Sundamage
  • Post Inflammatory Hyperpigmentation > Acne
  • Hormones > Melasma
  • Trauma > Injury
  • Sunglasses > Sun rays entering your iris telling your pituitary gland to make more pigment. 

These all send your skin’s melanin production cycle into extreme overdrive, causing your complexion to be muttled looking.

Ingredients that help control melanin production:

Azelaic Acid - A natural skin brightener found in wheat, rye and barley. Azelaic acid is most effective in concentrations of 20%, which is closely comparable in activity to 4% hydroquinone.

Licorice Root Extract - a great natural skin lightening alternative to chemical hydroquinone. It contains an active called glabridin, which inhibits tyrosinase, the enzyme that causes pigmentation in response to sun exposure.

Arbutin - made synthetically or derived from bearberry (uva-ursi) plant or Japanese mushrooms and exhibits antioxidant activity. works by breaking down into hydroquinone, it also has merit for improving the appearance of dark spots due to unprotected sun exposure or bodily changes such as can occur during pregnancy or due to other factors.

Niacinamide - commonly known as pro-vitamin B3, niacinamide is an antioxidant, sebum balancer, acne fighter, anti-inflammatory, ceramide booster and… a very effective skin lightening active. 

Mulberry Extract - This potent yet gentle, skin brightener lightens without causing irritation. It is very high in antioxidants and has strong melanogenesis inhibiting properties and in recent studies was shown to have nearly a 50% difference in decreasing hyperpigmentation over Hydroquinone.

Kojic Acid - a fungus that grows on fermented rice and soybeans and is also found in rice wine vinegar and sake. It has antibacterial properties and is a mild inhibitor of the formation of pigment in plant and animal tissues.

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